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  • Biomedsearch home advanced search tools search tutorial login | create free account document detail   interstitial lung disease associated with collagen vascular disorders: disease quantification using a computer-aided diagnosis tool. Medline citation: pmid:â  18726597 â â â  owner:â  nlm â â â  status:â  medline â â â  abstract/otherabstract: the purpose of this study was to evaluate a computer-aided diagnosis (cad) tool compared to human observers in quantification of interstitial lung disease (ild) in patients with collagen-vascular disorders. A total of 52 patients with rheumatoid arthritis (n=24), scleroderma (n=14) and systemic lupus erythematosus (n=14) underwent thin-section ct. Two independent observers assessed the extent of ild (eoild), reticulation (eoret) and ground-glass opacity (eoggo). Cad assessed eoild twice. Pulmonary function tests were obtained. Statistical evaluation used 95% limits of agreement and linear regression analysis. Cad correlated well with diffusing capacity (dl(co)) (r= -0. 531, p<0. 0001) and moderately with forced vital capacity (fvc) (r= -0. 483, p=0. 0008). There was close correlation between cad and the readers (eoild vs. Cad: r=0. viagra without a doctor prescription generic viagra online generic viagra online viagra for sale buy cheap viagra cheap generic viagra cheap viagra buy viagra online 716, p<0. 0001; eoret vs. Cad: r=0. 69, p<0. 0001). Subgroup analysis including patients with minimal eoggo (<15%) strengthened the correlations between cad and the readers, readers and pft, and cad and pft. Eoild by readers correlated strongly with dl(co) (r= -0. 705, p<0. 0001) and moderately with fvc (r= -0. 559, p=0. 0002). Eoret correlated closely with dl(co) and moderately with fvc (dl(co): r= -0. 663; fvc: r = -0. 436; p A-Frames
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